Negative-to-Positive Lymph Node Ratio as an Independent Prognostic Factor for Gastric Adenocarcinoma

OBJECTIVE To investigate the association between ratio of negative/positive lymph nodes (RNP) and other clinic pathological parameters. STUDY DESIGN Descriptive study. PLACE AND DURATION OF  Faculty Medicine, Cumhuriyet University, Sivas, Turkey, from February 2008 to December 2019. METHODOLOGY Consecutive 119 patients with gastric adenocarcinoma, who underwent gastrectomy D2 node dissection, were included. RNP, clinicopathological parameters such as tumour grade, type lymphovascular invasion (LVI) analysed, their prognostic impact was investigated. RESULTS RNP an independent factor for overall survival (p = 0.003) significantly associated poor <0.001). Advanced pathologic T N stage, presence perineural (PNI), LVI, high diffuse-type per Louren's classification, number negative also (all p <0.05). Although stage <0.01), PNI LVI classification grade <0.01) in univariate analyses; only gender 0.025), 0.037), 0.028), 0.006), of  meaningfully a multivariate analysis. CONCLUSION The can be used marker cancer, undergo curative resection, alternative stage. Key Words: Stomach neoplasms, Lymph ratio, Prognosis, Gastrectomy, nodes.